Professor Nic Bury's research interests are broad and includes aquatic toxicology, stress physiology and environmental monitoring. He supports the 3Rs (refinement, reduction and replacement) approach in animal research and part of his research includes the development of alternative test procedure for fish in toxicological studies. He is the current convenor for the Endocrine group of The Society for Experimental Biology and is also a member of the Society for Environmental Toxicology and Chemistry and The Fisheries Society of the British Isles.
Current research Interest
• Ecotoxicology (metals, pharmaceuticals, microplastics)
• Fish Physiology and adaptation to environmental pollution
• In vitro systems to assess bioaccumulation of chemicals in fish
• Evolution of the stress response system in vertebrates
• Sensor networks for environmental monitoring
Selection of recent publication (see www.burylabs.co.uk for full list):
Dohmann Chang, E., Hogstrand, C., Miller, T.H., Owen, S.F., Bury, N.R. 2019. The use of molecular descriptors to model pharmaceutical uptake by a fish primary gill cell culture epithelium. Environmental Science and Technology, in press. DOI: 10.1021/acs.est.8b04394.
Miller, TH; Gallidabino, MD; MacRae, JI; Owen, SF; Bury, NR; Barron, LP. 2019. Prediction of bioconcentration factors in fish and invertebrates using machine learning. Science of the Total Environment, 648, 80 – 89.
Miller, TH; Gallidabino, MD; MacRae, JI; Hogstrand, C; Bury, NR; Barron, LP; Snape, JR; Owen, SF. 2018. Machine Learning for Environmental Toxicology: A Call for Integration and Innovation. Environmental Science and Technology 52, 12953 – 12955.
Miller, T.H. Bury, N.R., Owen, S.F., McRae, J.I., Barron, L.P. 2018. A review of the pharmaceutical exosome in aquatic fauna. Environmental Pollution 239, 129-146.
Sneddon, L.U., Halsey, L.G., Bury, N.R. 2017. Considering aspects of the 3Rs principles within experimental animal biology. Journal for Experimental Biology, 220, 3007 – 3016.
Khan, F.R., Boyle, D., Chang, C., Bury, N.R. 2017. Do polyethylene microplastic beads alter the intestinal uptake of Ag in rainbow trout (Oncorhynchus mykiss)? Analysis of the MP vector effect using in vitro gut sacs. Environmental Pollution, 231, 200-206.
Clifford, A.M., Bury, N.R., Schultz, A.G., Ede, J.D., Goss, B.L., Goss, G.G. 2017. Regulation of plasma glucose and sulfate excretion in Pacific Hagfish, Eptatretus stoutii is not mediated by 11-deoxycortisol. General and Comparative Endocrinology, 247, 107-115.
Bury, N.R. 2017. The evolution, structure and function of the ray finned fish (Actinopterygii) glucocorticoid receptors. General and Comparative Endocrinology, 251, 4 - 11
Schnell, S., Stott, L.C., Hogstrand, C., Wood, C.M., Kelly, S.P., Part, P., Owen, S.F., Bury N.R. 2016. Procedures for the reconstruction, primary culture and experimental use of rainbow trout epithelia. Nature Protocols 11, 490-498.