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Functional Gastrointestinal Disorders: A Spectrum of Food Intolerances

Researcher: Dr Fandi Ibrahim

Functional gastrointestinal disorders (FGDs) affect around 20% of the population worldwide and are associated with reduced quality of life and increased healthcare costs. Dietary therapies are frequently implemented to assist with symptom relief in these individuals, but concerns exist regarding their complexity, restrictiveness, nutritional adequacy, and effectiveness. 

Therefore, a novel approach, the 5Ad Dietary Protocol, was designed to overcome the above issues, and is currently under investigation for its efficacy in reducing the severity of FGDs as well as compliance matters. The protocol was designed by theorising that FGDs are a form of food intolerances, due to significant changes which have occurred from the pre-post agricultural era, and was then evaluated in a repeated measures MANOVA design employing six abdominal symptom measures, monitored during a baseline week (participants’ habitual diet) and an intervention week (following the 5Ad Dietary Protocol). With the success of the first phase (https://pubmed.ncbi.nlm.nih.gov/31426496/), we are planning a Randomised Control Trial (RCT) study against a sham protocol and expanding on the participants long-term adherence for such way of eating in people with FBGs.

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Breakfast bowl with bananas, blueberries and walnuts.